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The stability of cylindrin β-barrel amyloid oligomer models – a molecular dynamics study

Small soluble amyloid oligomers are believed to play a significant role in the pathology of amyloid diseases. Recently, the atomic structure of a toxic oligomer formed by an 11 residue and its tandem repeat was found to have an out-off register antiparallel β-strands in the shape of a β-barrel. In t...

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Библиографические подробности
Главные авторы: Berhanu, Workalemahu M., Hansmann, Ulrich H. E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206217/
https://ncbi.nlm.nih.gov/pubmed/23606599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24302
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