Notch modulates VEGF action in endothelial cells by inducing Matrix Metalloprotease activity

BACKGROUND: In the vasculature, Notch signaling functions as a downstream effecter of Vascular Endothelial Growth Factor (VEGF) signaling. VEGF regulates sprouting angiogenesis in part by inducing and activating matrix metalloproteases (MMPs). This study sought to determine if VEGF regulation of MMP...

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Main Authors: Funahashi, Yasuhiro, Shawber, Carrie J, Sharma, Anshula, Kanamaru, Emi, Choi, Yun K, Kitajewski, Jan
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039832/
https://ncbi.nlm.nih.gov/pubmed/21349159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-3-2
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