Notch modulates VEGF action in endothelial cells by inducing Matrix Metalloprotease activity

BACKGROUND: In the vasculature, Notch signaling functions as a downstream effecter of Vascular Endothelial Growth Factor (VEGF) signaling. VEGF regulates sprouting angiogenesis in part by inducing and activating matrix metalloproteases (MMPs). This study sought to determine if VEGF regulation of MMP...

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Bibliografiske detaljer
Main Authors: Funahashi, Yasuhiro, Shawber, Carrie J, Sharma, Anshula, Kanamaru, Emi, Choi, Yun K, Kitajewski, Jan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039832/
https://ncbi.nlm.nih.gov/pubmed/21349159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-3-2
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