A Notch1 Ectodomain Construct Inhibits Endothelial Notch Signaling, Tumor Growth, and Angiogenesis

Notch signaling is required for vascular development and tumor angiogenesis. Although inhibition of the Notch ligand Delta-like 4 can restrict tumor growth and disrupt neo-vasculature, the effect of inhibiting Notch receptor function on angiogenesis has yet to be defined. In this study, we generated...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Funahashi, Yasuhiro, Hernandez, Sonia L., Das, Indranil, Ahn, Audrey, Huang, Jianzhong, Vorontchikhina, Marina, Sharma, Anshula, Kanamaru, Emi, Borisenko, Valeriya, DeSilva, Dinuka M., Suzuki, Akihiko, Wang, Xing, Shawber, Carrie J., Kandel, Jessica J., Yamashiro, Darrell J., Kitajewski, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690602/
https://ncbi.nlm.nih.gov/pubmed/18559519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6499
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados