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Notch1 functions as a negative regulator of lymphatic endothelial cell differentiation in the venous endothelium
In development, lymphatic endothelial cells originate within veins and differentiate via a process requiring Prox1. Notch signaling regulates cell-fate decisions, and expression studies suggested that Jag1/Notch1 signaling functions in veins during lymphatic endothelial specification. Using an induc...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Company of Biologists
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3653558/ https://ncbi.nlm.nih.gov/pubmed/23615281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.083865 |
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