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Notch1 functions as a negative regulator of lymphatic endothelial cell differentiation in the venous endothelium

In development, lymphatic endothelial cells originate within veins and differentiate via a process requiring Prox1. Notch signaling regulates cell-fate decisions, and expression studies suggested that Jag1/Notch1 signaling functions in veins during lymphatic endothelial specification. Using an induc...

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Detalhes bibliográficos
Main Authors: Murtomaki, Aino, Uh, Minji K., Choi, Yun K., Kitajewski, Christopher, Borisenko, Valeriya, Kitajewski, Jan, Shawber, Carrie J.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653558/
https://ncbi.nlm.nih.gov/pubmed/23615281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.083865
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