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Crystal structure of arrestin-3 reveals the basis of the difference in receptor binding between two non-visual subtypes
Arrestins are multi-functional proteins that regulate signaling and trafficking of the majority of G protein-coupled receptors (GPCRs), as well as sub-cellular localization and activity of many other signaling proteins. Here we report the first crystal structure of arrestin-3, solved at 3.0Å. Arrest...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3034793/ https://ncbi.nlm.nih.gov/pubmed/21215759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.12.034 |
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