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Crystal structure of arrestin-3 reveals the basis of the difference in receptor binding between two non-visual subtypes

Arrestins are multi-functional proteins that regulate signaling and trafficking of the majority of G protein-coupled receptors (GPCRs), as well as sub-cellular localization and activity of many other signaling proteins. Here we report the first crystal structure of arrestin-3, solved at 3.0Å. Arrest...

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Autors principals: Zhan, Xuanzhi, Gimenez, Luis E., Gurevich, Vsevolod V., Spiller, Benjamin W.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034793/
https://ncbi.nlm.nih.gov/pubmed/21215759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.12.034
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