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Identification of Receptor Binding-induced Conformational Changes in Non-visual Arrestins

The non-visual arrestins, arrestin-2 and arrestin-3, belong to a small family of multifunctional cytosolic proteins. Non-visual arrestins interact with hundreds of G protein-coupled receptors (GPCRs) and regulate GPCR desensitization by binding active phosphorylated GPCRs and uncoupling them from he...

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Autori principali: Zhuo, Ya, Vishnivetskiy, Sergey A., Zhan, Xuanzhi, Gurevich, Vsevolod V., Klug, Candice S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110305/
https://ncbi.nlm.nih.gov/pubmed/24867953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.560680
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