An eight amino acid segment controls oligomerization and preferred conformation of the two non-visual arrestins

G protein coupled receptors signal through G proteins or arrestins. A long-standing mystery in the field is why vertebrates have two non-visual arrestins, arrestin-2 and arrestin-3. These isoforms are ~75% identical and 85% similar; each binds numerous receptors, and appear to have many redundant fu...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Chen, Qiuyan, Zhuo, Ya, Sharma, Pankaj, Perez, Ivette, Francis, Derek J., Chakravarthy, Srinivas, Vishnivetskiy, Sergey A., Berndt, Sandra, Hanson, Susan M., Zhan, Xuanzhi, Brooks, Evan K., Altenbach, Christian, Hubbell, Wayne L., Klug, Candice S., Iverson, T. M., Gurevich, Vsevolod V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870585/
https://ncbi.nlm.nih.gov/pubmed/33387531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.166790
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