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An eight amino acid segment controls oligomerization and preferred conformation of the two non-visual arrestins

G protein coupled receptors signal through G proteins or arrestins. A long-standing mystery in the field is why vertebrates have two non-visual arrestins, arrestin-2 and arrestin-3. These isoforms are ~75% identical and 85% similar; each binds numerous receptors, and appear to have many redundant fu...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:	J Mol Biol
Κύριοι συγγραφείς:	Chen, Qiuyan, Zhuo, Ya, Sharma, Pankaj, Perez, Ivette, Francis, Derek J., Chakravarthy, Srinivas, Vishnivetskiy, Sergey A., Berndt, Sandra, Hanson, Susan M., Zhan, Xuanzhi, Brooks, Evan K., Altenbach, Christian, Hubbell, Wayne L., Klug, Candice S., Iverson, T. M., Gurevich, Vsevolod V.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	2020
Θέματα:	Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7870585/ https://ncbi.nlm.nih.gov/pubmed/33387531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.166790
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An eight amino acid segment controls oligomerization and preferred conformation of the two non-visual arrestins

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