An eight amino acid segment controls oligomerization and preferred conformation of the two non-visual arrestins

G protein coupled receptors signal through G proteins or arrestins. A long-standing mystery in the field is why vertebrates have two non-visual arrestins, arrestin-2 and arrestin-3. These isoforms are ~75% identical and 85% similar; each binds numerous receptors, and appear to have many redundant fu...

Full description

Saved in:
Bibliographic Details
Published in:J Mol Biol
Main Authors: Chen, Qiuyan, Zhuo, Ya, Sharma, Pankaj, Perez, Ivette, Francis, Derek J., Chakravarthy, Srinivas, Vishnivetskiy, Sergey A., Berndt, Sandra, Hanson, Susan M., Zhan, Xuanzhi, Brooks, Evan K., Altenbach, Christian, Hubbell, Wayne L., Klug, Candice S., Iverson, T. M., Gurevich, Vsevolod V.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870585/
https://ncbi.nlm.nih.gov/pubmed/33387531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.166790
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items