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Risperidone-Induced Inactivation and Clozapine-Induced Reactivation of Rat Cortical Astrocyte 5-Hydroxytryptamine(7) Receptors: Evidence for In Situ G Protein-Coupled Receptor Homodimer Protomer Cross-Talk
We have reported previously novel drug-induced inactivation and reactivation of human 5-hydroxytryptamine(7) (5-HT(7)) receptors in a recombinant cell line. To explain these novel observations, a homodimer structure displaying protomer-protomer cross-talk was proposed. To determine whether these nov...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033711/ https://ncbi.nlm.nih.gov/pubmed/21062995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.069278 |
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