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Risperidone-Induced Inactivation and Clozapine-Induced Reactivation of Rat Cortical Astrocyte 5-Hydroxytryptamine(7) Receptors: Evidence for In Situ G Protein-Coupled Receptor Homodimer Protomer Cross-Talk

We have reported previously novel drug-induced inactivation and reactivation of human 5-hydroxytryptamine(7) (5-HT(7)) receptors in a recombinant cell line. To explain these novel observations, a homodimer structure displaying protomer-protomer cross-talk was proposed. To determine whether these nov...

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Detalhes bibliográficos
Main Authors: Smith, Carol, Toohey, Nicole, Knight, Jessica A., Klein, Michael T., Teitler, Milt
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033711/
https://ncbi.nlm.nih.gov/pubmed/21062995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.069278
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