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Toward Selective Drug Development for the Human 5-Hydroxytryptamine 1E Receptor: A Comparison of 5-Hydroxytryptamine 1E and 1F Receptor Structure-Affinity Relationships

The 5-hydroxytryptamine (5-HT) 1E receptor is highly expressed in the human frontal cortex and hippocampus, and this distribution suggests the function of 5-HT(1E) receptors might be linked to memory. To test this hypothesis, behavioral experiments are needed. Because rats and mice lack a 5-HT(1E) r...

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Detalhes bibliográficos
Main Authors: Klein, Michael T., Dukat, Małgorzata, Glennon, Richard A., Teitler, Milt
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101003/
https://ncbi.nlm.nih.gov/pubmed/21422162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.179606
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