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Pharmacological Analysis of the Novel, Rapid, and Potent Inactivation of the Human 5-Hydroxytryptamine(7) Receptor by Risperidone, 9-OH-Risperidone, and Other Inactivating Antagonists

In a previous publication, using human 5-hydroxytryptamine(7) (h5-HT(7)) receptor-expressing human embryonic kidney (HEK) 293 cells, we reported the rapid, potent inactivation of the h5-HT(7) receptor stimulation of cAMP production by three antagonists: risperidone, 9-OH-risperidone, and methiothepi...

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Detalhes bibliográficos
Main Authors: Knight, Jessica A., Smith, Carol, Toohey, Nicole, Klein, Michael T., Teitler, Milt
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671286/
https://ncbi.nlm.nih.gov/pubmed/18996971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.052084
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