Human 5-HT(7) Receptor-Induced Inactivation of Forskolin-Stimulated Adenylate Cyclase by Risperidone, 9-OH-Risperidone and Other “Inactivating Antagonists”

We have previously reported on the unusual human 5-hydroxytryptamine(7) (h5-HT(7)) receptor-inactivating properties of risperidone, 9-OH-risperidone, bromocriptine, methiothepin, metergoline, and lisuride. Inactivation was defined as the inability of 10 μM 5-HT to stimulate cAMP accumulation after b...

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Main Authors: Toohey, Nicole, Klein, Michael T., Knight, Jessica, Smith, Carol, Teitler, Milt
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730387/
https://ncbi.nlm.nih.gov/pubmed/19509219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.056283
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