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Varenicline Is a Potent Agonist of the Human 5-Hydroxytryptamine(3) Receptor

Varenicline, a widely used and successful smoking cessation agent, acts as a partial agonist at nicotinic acetylcholine receptors. Here, we explore the effects of varenicline at human and mouse 5-Hydroxytryptamine(3) (5-HT(3)) receptors. Application of varenicline to human 5-HT(3) receptors expresse...

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Hlavní autoři: Lummis, S. C. R., Thompson, A. J., Bencherif, M., Lester, H. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186289/
https://ncbi.nlm.nih.gov/pubmed/21775477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.185306
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