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Colchicine: A Novel Positive Allosteric Modulator of the Human 5-Hydroxytryptamine(3A) Receptor

The actions of colchicine were examined with the two-electrode voltage-clamp technique and radioligand binding assays in mouse and human 5-hydroxytryptamine(3A) receptors (5-HT(3A)Rs) expressed in Xenopus laevis oocytes. Colchicine inhibited 5-hydroxytryptamine (5-HT)-evoked currents in oocytes expr...

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Detalles Bibliográficos
Main Authors: de Oliveira-Pierce, A. N., Zhang, R., Machu, T. K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Pharmacology and Experimental Therapeutics 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672862/
https://ncbi.nlm.nih.gov/pubmed/19188483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.146522
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