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A Substituted Anilino Enaminone Acts as a Novel Positive Allosteric Modulator of GABA(A) Receptors in the Mouse Brain
A small library of anilino enaminones was analyzed for potential anticonvulsant agents. We examined the effects of three anilino enaminones on neuronal activity of output neurons, mitral cells (MC), in an olfactory bulb brain slice preparation using whole-cell patch-clamp recording. These compounds...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061544/ https://ncbi.nlm.nih.gov/pubmed/21163867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.173740 |
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