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A Substituted Anilino Enaminone Acts as a Novel Positive Allosteric Modulator of GABA(A) Receptors in the Mouse Brain
A small library of anilino enaminones was analyzed for potential anticonvulsant agents. We examined the effects of three anilino enaminones on neuronal activity of output neurons, mitral cells (MC), in an olfactory bulb brain slice preparation using whole-cell patch-clamp recording. These compounds...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061544/ https://ncbi.nlm.nih.gov/pubmed/21163867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.173740 |
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