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A Substituted Anilino Enaminone Acts as a Novel Positive Allosteric Modulator of GABA(A) Receptors in the Mouse Brain

A small library of anilino enaminones was analyzed for potential anticonvulsant agents. We examined the effects of three anilino enaminones on neuronal activity of output neurons, mitral cells (MC), in an olfactory bulb brain slice preparation using whole-cell patch-clamp recording. These compounds...

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Bibliografiset tiedot
Päätekijät: Wang, Ze-Jun, Sun, Liqin, Jackson, Patrice L., Scott, Kenneth R., Heinbockel, Thomas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Pharmacology and Experimental Therapeutics 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061544/
https://ncbi.nlm.nih.gov/pubmed/21163867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.173740
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