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Inhibition of Recombinant L-Type Voltage-Gated Calcium Channels by Positive Allosteric Modulators of GABA(A) Receptors

Benzodiazepines (BDZs) depress neuronal excitability via positive allosteric modulation of inhibitory GABA(A) receptors (GABA(A)R). BDZs and other positive GABA(A)R modulators, including barbiturates, ethanol, and neurosteroids, can also inhibit L-type voltage-gated calcium channels (L-VGCCs), which...

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Autori principali: Earl, Damien E., Tietz, Elizabeth I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063747/
https://ncbi.nlm.nih.gov/pubmed/21262851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.178244
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