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Inhibition of Recombinant L-Type Voltage-Gated Calcium Channels by Positive Allosteric Modulators of GABA(A) Receptors

Benzodiazepines (BDZs) depress neuronal excitability via positive allosteric modulation of inhibitory GABA(A) receptors (GABA(A)R). BDZs and other positive GABA(A)R modulators, including barbiturates, ethanol, and neurosteroids, can also inhibit L-type voltage-gated calcium channels (L-VGCCs), which...

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Hlavní autoři: Earl, Damien E., Tietz, Elizabeth I.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063747/
https://ncbi.nlm.nih.gov/pubmed/21262851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.178244
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