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Recognition of Sulfonylurea Receptor (ABCC8/9) Ligands by the Multidrug Resistance Transporter P-glycoprotein (ABCB1): FUNCTIONAL SIMILARITIES BASED ON COMMON STRUCTURAL FEATURES BETWEEN TWO MULTISPECIFIC ABC PROTEINS
ATP-sensitive K(+) (K(ATP)) channels are the target of a number of pharmacological agents, blockers like hypoglycemic sulfonylureas and openers like the hypotensive cromakalim and diazoxide. These agents act on the channel regulatory subunit, the sulfonylurea receptor (SUR), which is an ABC protein...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3030360/ https://ncbi.nlm.nih.gov/pubmed/21098040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155200 |
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