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Recognition of Sulfonylurea Receptor (ABCC8/9) Ligands by the Multidrug Resistance Transporter P-glycoprotein (ABCB1): FUNCTIONAL SIMILARITIES BASED ON COMMON STRUCTURAL FEATURES BETWEEN TWO MULTISPECIFIC ABC PROTEINS

ATP-sensitive K(+) (K(ATP)) channels are the target of a number of pharmacological agents, blockers like hypoglycemic sulfonylureas and openers like the hypotensive cromakalim and diazoxide. These agents act on the channel regulatory subunit, the sulfonylurea receptor (SUR), which is an ABC protein...

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Bibliografiska uppgifter
Huvudupphovsmän:	Bessadok, Anis, Garcia, Elisabeth, Jacquet, Hélène, Martin, Solenne, Garrigues, Alexia, Loiseau, Nicolas, André, François, Orlowski, Stéphane, Vivaudou, Michel
Materialtyp:	Artigo
Språk:	Inglês
Publicerad:	American Society for Biochemistry and Molecular Biology 2011
Ämnen:	Enzymology
Länkar:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3030360/ https://ncbi.nlm.nih.gov/pubmed/21098040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155200
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Recognition of Sulfonylurea Receptor (ABCC8/9) Ligands by the Multidrug Resistance Transporter P-glycoprotein (ABCB1): FUNCTIONAL SIMILARITIES BASED ON COMMON STRUCTURAL FEATURES BETWEEN TWO MULTISPECIFIC ABC PROTEINS

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