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Understanding polyspecificity of multidrug ABC transporters: closing in on the gaps in ABCB1
Multidrug ABC transporters can transport a wide range of drugs from the cell. Ongoing studies of the prototype mammalian multidrug resistance ATP-binding cassette transporter P-glycoprotein (ABCB1) have revealed many intriguing functional and biochemical features. However, a gap remains in our knowl...
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Publicado no: | Trends Biochem Sci |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608440/ https://ncbi.nlm.nih.gov/pubmed/19819701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2009.07.009 |
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