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Distinct Conformational Spectrum of Homologous Multidrug ABC Transporters

ATP-binding cassette (ABC) exporters are ubiquitously found in all kingdoms of life and their members play significant roles in mediating drug pharmacokinetics and multidrug resistance in the clinic. Significant questions and controversies remain regarding the relevance of their conformations observ...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Moeller, Arne, Lee, Sung Chang, Tao, Houchao, Speir, Jeffrey A., Chang, Geoffrey, Urbatsch, Ina L., Potter, Clinton S., Carragher, Bridget, Zhang, Qinghai
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351144/
https://ncbi.nlm.nih.gov/pubmed/25661651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.12.013
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