Engineered Nanostructured β-Sheet Peptides Protect Membrane Proteins

We have designed β-strand peptides (BP) that stabilize integral membrane proteins (IMP). BPs self-assemble in solution as filaments and become restructured upon association with IMPs; the resulting IMP/BP complexes resist aggregation when diluted in detergent-free buffer and are examined as stable,...

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Main Authors: Tao, Houchao, Lee, Sung Chang, Moeller, Arne, Roy, Rituparna Sinha, Siu, Fai Yiu, Zimmermann, Jörg, Stevens, Raymond C., Potter, Clinton S., Carragher, Bridget, Zhang, Qinghai
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753066/
https://ncbi.nlm.nih.gov/pubmed/23817067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2533
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