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αENaC-Mediated Lithium Absorption Promotes Nephrogenic Diabetes Insipidus
Lithium-induced nephrogenic diabetes insipidus (NDI) is accompanied by polyuria, downregulation of aquaporin 2 (AQP2), and cellular remodeling of the collecting duct (CD). The amiloride-sensitive epithelial sodium channel (ENaC) is a likely candidate for lithium entry. Here, we subjected transgenic...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Nephrology
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3029898/ https://ncbi.nlm.nih.gov/pubmed/21051735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010070734 |
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