Collecting duct–specific gene inactivation of αENaC in the mouse kidney does not impair sodium and potassium balance

Aldosterone controls the final sodium reabsorption and potassium secretion in the kidney by regulating the activity of the epithelial sodium channel (ENaC) in the aldosterone-sensitive distal nephron (ASDN). ASDN consists of the last portion of the distal convoluted tubule (late DCT), the connecting...

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Main Authors: Rubera, Isabelle, Loffing, Johannes, Palmer, Lawrence G., Frindt, Gustavo, Fowler-Jaeger, Nicole, Sauter, Daniel, Carroll, Tom, McMahon, Andrew, Hummler, Edith, Rossier, Bernard C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2003
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC171384/
https://ncbi.nlm.nih.gov/pubmed/12925696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316956
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