Plasma Potassium Determines NCC Abundance in Adult Kidney-Specific γENaC Knockout

The amiloride-sensitive epithelial sodium channel (ENaC) and the thiazide-sensitive sodium chloride cotransporter (NCC) are key regulators of sodium and potassium and colocalize in the late distal convoluted tubule of the kidney. Loss of the αENaC subunit leads to a perinatal lethal phenotype charac...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Am Soc Nephrol
Auteurs principaux: Boscardin, Emilie, Perrier, Romain, Sergi, Chloé, Maillard, Marc P., Loffing, Johannes, Loffing-Cueni, Dominique, Koesters, Robert, Rossier, Bernard C., Hummler, Edith
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2018
Sujets:
Basic Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827588/
https://ncbi.nlm.nih.gov/pubmed/29371419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017030345
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