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Nitric oxide reduces Cl(−) absorption in the mouse cortical collecting duct through an ENaC-dependent mechanism

Since nitric oxide (NO) participates in the renal regulation of blood pressure, in part, by modulating transport of Na(+) and Cl(−) in the kidney, we asked whether NO regulates net Cl(−) flux (J(Cl)) in the cortical collecting duct (CCD) and determined the transporter(s) that mediate NO-sensitive Cl...

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Detalhes bibliográficos
Main Authors: Pech, Vladimir, Thumova, Monika, Dikalov, Sergey I., Hummler, Edith, Rossier, Bernard C., Harrison, David G., Wall, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680692/
https://ncbi.nlm.nih.gov/pubmed/23515718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00292.2012
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