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ENaC inhibition stimulates Cl(−) secretion in the mouse cortical collecting duct through an NKCC1-dependent mechanism
In cortical collecting ducts (CCDs) perfused in vitro, inhibiting the epithelial Na(+) channel (ENaC) reduces Cl(−) absorption. Since ENaC does not transport Cl(−), the purpose of this study was to determine how ENaC modulates Cl(−) absorption. Thus, Cl(−) absorption was measured in CCDs perfused in...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Physiological Society
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3431594/ https://ncbi.nlm.nih.gov/pubmed/22496413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00030.2012 |
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