Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4

Cardiac pacemaking generation and modulation rely on the coordinated activity of several processes. Although a wealth of evidence indicates a relevant role of the I(f) (“funny,” or pacemaker) current, whose molecular constituents are the hyperpolarization-activated, cyclic nucleotide-gated (HCN) cha...

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Detalhes bibliográficos
Main Authors: Baruscotti, Mirko, Bucchi, Annalisa, Viscomi, Carlo, Mandelli, Giacomo, Consalez, Giacomo, Gnecchi-Rusconi, Tomaso, Montano, Nicola, Casali, Karina Rabello, Micheloni, Stefano, Barbuti, Andrea, DiFrancesco, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029742/
https://ncbi.nlm.nih.gov/pubmed/21220308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010122108
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