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Properties of ivabradine-induced block of HCN1 and HCN4 pacemaker channels
Ivabradine is a ‘heart rate-reducing’ agent able to slow heart rate, without complicating side-effects. Its action results from a selective and specific block of pacemaker f-channels of the cardiac sinoatrial node (SAN). Investigation has shown that block by ivabradine requires open f-channels, is u...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Blackwell Science Inc
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1779671/ https://ncbi.nlm.nih.gov/pubmed/16484306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.100776 |
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