The NLRP3 inflammasome plays key role in the regulation of intestinal homeostasis

Attenuated innate immune responses to the intestinal microbiota have been linked to the pathogenesis of Crohn’s disease (CD). Recent genetic studies have revealed that hypofunctional mutations of NLRP3, a member of the NOD-like receptor (NLR) superfamily, are associated with an increased risk of dev...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hirota, Simon A., Ng, Jeffrey, Lueng, Alan, Khajah, Maitham, Parhar, Ken, Li, Yan, Lam, Victor, Potentier, Mireille S., Ng, Kelvin, Bawa, Misha, McCafferty, Donna-Marie, Rioux, Kevin P., Ghosh, Subrata, Xavier, Ramnik J., Colgan, Sean P., Tschopp, Jurg, Muruve, Daniel, MacDonald, Justin A., Beck, Paul L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026862/
https://ncbi.nlm.nih.gov/pubmed/20872834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21478
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