The NLRP3 inflammasome plays key role in the regulation of intestinal homeostasis

Attenuated innate immune responses to the intestinal microbiota have been linked to the pathogenesis of Crohn’s disease (CD). Recent genetic studies have revealed that hypofunctional mutations of NLRP3, a member of the NOD-like receptor (NLR) superfamily, are associated with an increased risk of dev...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Hirota, Simon A., Ng, Jeffrey, Lueng, Alan, Khajah, Maitham, Parhar, Ken, Li, Yan, Lam, Victor, Potentier, Mireille S., Ng, Kelvin, Bawa, Misha, McCafferty, Donna-Marie, Rioux, Kevin P., Ghosh, Subrata, Xavier, Ramnik J., Colgan, Sean P., Tschopp, Jurg, Muruve, Daniel, MacDonald, Justin A., Beck, Paul L.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026862/
https://ncbi.nlm.nih.gov/pubmed/20872834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21478
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki