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Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity

FEN1, a key participant in DNA replication and repair, is the major human flap endonuclease that recognizes and cleaves flap DNA structures. Deficiencies in FEN1 function or deletion of the fen1 gene have profound biological effects, including the suppression of repair of DNA damage incurred from th...

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Autors principals: Dorjsuren, Dorjbal, Kim, Daemyung, Maloney, David J., Wilson, David M., Simeonov, Anton
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025571/
https://ncbi.nlm.nih.gov/pubmed/21062821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1082
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