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Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity

FEN1, a key participant in DNA replication and repair, is the major human flap endonuclease that recognizes and cleaves flap DNA structures. Deficiencies in FEN1 function or deletion of the fen1 gene have profound biological effects, including the suppression of repair of DNA damage incurred from th...

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Detalhes bibliográficos
Main Authors: Dorjsuren, Dorjbal, Kim, Daemyung, Maloney, David J., Wilson, David M., Simeonov, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025571/
https://ncbi.nlm.nih.gov/pubmed/21062821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1082
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