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Identification and Characterization of Inhibitors of Human Apurinic/apyrimidinic Endonuclease APE1
APE1 is the major nuclease for excising abasic (AP) sites and particular 3′-obstructive termini from DNA, and is an integral participant in the base excision repair (BER) pathway. BER capacity plays a prominent role in dictating responsiveness to agents that generate oxidative or alkylation DNA dama...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685009/ https://ncbi.nlm.nih.gov/pubmed/19484131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005740 |
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