A highly conserved SOX6 double binding site mediates SOX6 gene downregulation in erythroid cells

The Sox6 transcription factor plays critical roles in various cell types, including erythroid cells. Sox6-deficient mice are anemic due to impaired red cell maturation and show inappropriate globin gene expression in definitive erythrocytes. To identify new Sox6 target genes in erythroid cells, we u...

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Hlavní autoři: Cantu', Claudio, Grande, Vito, Alborelli, Ilaria, Cassinelli, Letizia, Cantu’, Ileana, Colzani, Maria Teresa, Ierardi, Rossella, Ronzoni, Luisa, Cappellini, Maria Domenica, Ferrari, Giuliana, Ottolenghi, Sergio, Ronchi, Antonella
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Gene Regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025548/
https://ncbi.nlm.nih.gov/pubmed/20852263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq819
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