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The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis

SOX9 is a transcriptional activator required for chondrogenesis, and SOX5 and SOX6 are closely related DNA-binding proteins that critically enhance its function. We use here genome-wide approaches to gain novel insights into the full spectrum of the target genes and modes of action of this chondroge...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Liu, Chia-Feng, Lefebvre, Véronique
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787819/
https://ncbi.nlm.nih.gov/pubmed/26150426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv688
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