Unravelling pathways downstream Sox6 induction in K562 erythroid cells by proteomic analysis

The Sox6 transcription factor is crucial for terminal maturation of definitive red blood cells. Sox6-null mouse fetuses present misshapen and nucleated erythrocytes, due to impaired actin assembly and cytoskeleton stability. These defects are accompanied with a reduced survival of Sox6(−/−) red bloo...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Barbarani, Gloria, Ronchi, Antonella, Ruoppolo, Margherita, Santorelli, Lucia, Steinfelder, Robert, Elangovan, Sudharshan, Fugazza, Cristina, Caterino, Marianna
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658338/
https://ncbi.nlm.nih.gov/pubmed/29074889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14336-6
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