Emx2 is a dose-dependent negative regulator of Sox2 telencephalic enhancers

The transcription factor Sox2 is essential for neural stem cells (NSC) maintenance in the hippocampus and in vitro. The transcription factor Emx2 is also critical for hippocampal development and NSC self-renewal. Searching for ‘modifier’ genes affecting the Sox2 deficiency phenotype in mouse, we obs...

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Detalles Bibliográficos
Main Authors: Mariani, J., Favaro, R., Lancini, C., Vaccari, G., Ferri, A. L., Bertolini, J., Tonoli, D., Latorre, E., Caccia, R., Ronchi, A., Ottolenghi, S., Miyagi, S., Okuda, A., Zappavigna, V., Nicolis, S. K.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413107/
https://ncbi.nlm.nih.gov/pubmed/22495934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks295
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