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Defective erythroid maturation in gelsolin mutant mice

BACKGROUND: During late differentiation, erythroid cells undergo profound changes involving actin filament remodeling. One of the proteins controlling actin dynamics is gelsolin, a calcium-activated actin filament severing and capping protein. Gelsolin-null (Gsn(−/−)) mice generated in a C57BL/6 bac...

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Bibliografische gegevens
Hoofdauteurs: Cantù, Claudio, Bosè, Francesca, Bianchi, Paola, Reali, Eva, Colzani, Maria Teresa, Cantù, Ileana, Barbarani, Gloria, Ottolenghi, Sergio, Witke, Walter, Spinardi, Laura, Ronchi, Antonella Ellena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ferrata Storti Foundation 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396666/
https://ncbi.nlm.nih.gov/pubmed/22271892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.052522
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