BMP Signaling Modulates Hepcidin Expression in Zebrafish Embryos Independent of Hemojuvelin

Hemojuvelin (Hjv), a member of the repulsive-guidance molecule (RGM) family, upregulates transcription of the iron regulatory hormone hepcidin by activating the bone morphogenetic protein (BMP) signaling pathway in mammalian cells. Mammalian models have identified furin, neogenin, and matriptase-2 a...

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Autors principals: Gibert, Yann, Lattanzi, Victoria J., Zhen, Aileen W., Vedder, Lea, Brunet, Frédéric, Faasse, Sarah A., Babitt, Jodie L., Lin, Herbert Y., Hammerschmidt, Matthias, Fraenkel, Paula G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024971/
https://ncbi.nlm.nih.gov/pubmed/21283739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014553
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