BMP-6 is a key endogenous regulator of hepcidin expression and iron metabolism

Juvenile hemochromatosis is an iron overload disorder caused by mutations in the genes encoding the major iron regulatory hormone hepcidin (HAMP)1 and hemojuvelin (HFE2)2. We have previously shown that hemojuvelin is a bone morphogenetic protein (BMP) co-receptor and that BMP signals regulate hepcid...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Andriopoulos, Billy, Corradini, Elena, Xia, Yin, Faasse, Sarah A., Chen, Shanzhuo, Grgurevic, Lovorka, Knutson, Mitchell D., Pietrangelo, Antonello, Vukicevic, Slobodan, Lin, Herbert Y., Babitt, Jodie L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810136/
https://ncbi.nlm.nih.gov/pubmed/19252486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.335
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk