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Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice

The bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway is a central regulator of hepcidin expression and systemic iron balance. However, the molecular mechanisms by which iron is sensed to regulate BMP6-SMAD signaling and hepcidin expression are unknown. Here, we examined the effects of circ...

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Detalhes bibliográficos
Main Authors: Corradini, Elena, Meynard, Delphine, Wu, Qifang, Chen, Shan, Ventura, Paolo, Pietrangelo, Antonello, Babitt, Jodie L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277401/
https://ncbi.nlm.nih.gov/pubmed/21488083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24359
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