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Altered hepatic BMP signaling pathway in human HFE hemochromatosis
Human hemochromatosis (HC) has been associated with the common C282Y polymorphism of HFE or rare pathogenic mutations of TfR2, HJV, FPN and HAMP. All forms of human HC seem to be caused by low or inadequate levels of hepcidin, the iron hormone. We and others have recently shown that Hfe(−/−)mice exh...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3295241/ https://ncbi.nlm.nih.gov/pubmed/20863724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2010.08.010 |
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