BMP Signaling Modulates Hepcidin Expression in Zebrafish Embryos Independent of Hemojuvelin

Hemojuvelin (Hjv), a member of the repulsive-guidance molecule (RGM) family, upregulates transcription of the iron regulatory hormone hepcidin by activating the bone morphogenetic protein (BMP) signaling pathway in mammalian cells. Mammalian models have identified furin, neogenin, and matriptase-2 a...

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Detalhes bibliográficos
Main Authors: Gibert, Yann, Lattanzi, Victoria J., Zhen, Aileen W., Vedder, Lea, Brunet, Frédéric, Faasse, Sarah A., Babitt, Jodie L., Lin, Herbert Y., Hammerschmidt, Matthias, Fraenkel, Paula G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024971/
https://ncbi.nlm.nih.gov/pubmed/21283739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014553
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