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Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin

Hemojuvelin (HJV) is a coreceptor for bone morphogenetic protein (BMP) signaling that regulates hepcidin expression and iron metabolism. However, the precise combinations of BMP ligands and receptors used by HJV remain unknown. HJV has also been demonstrated to bind to neogenin, but it is not known...

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Detalhes bibliográficos
Main Authors: Xia, Yin, Babitt, Jodie L., Sidis, Yisrael, Chung, Raymond T., Lin, Herbert Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384142/
https://ncbi.nlm.nih.gov/pubmed/18326817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-111567
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