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Ribosomal biogenesis induction by high glucose requires activation of upstream binding factor in kidney glomerular epithelial cells

Diabetes promotes protein synthesis to induce kidney hypertrophy and increase renal matrix proteins. Increased capacity for mRNA translation by way of ribosomal biogenesis facilitates sustained stimulation of protein synthesis. We tested the hypothesis that high glucose induces ribosomal biogenesis...

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Detalhes bibliográficos
Main Authors: Mariappan, Meenalakshmi M., D'Silva, Kristin, Lee, Myung Ja, Sataranatarajan, Kavithalakshmi, Barnes, Jeffrey L., Choudhury, Goutam Ghosh, Kasinath, Balakuntalam S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023218/
https://ncbi.nlm.nih.gov/pubmed/20943765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00207.2010
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