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Regulation of Elongation Phase of mRNA Translation in Diabetic Nephropathy : Amelioration by Rapamycin
High glucose and high insulin, pathogenic factors in type 2 diabetes, induce rapid synthesis of the matrix protein laminin-β1 in renal proximal tubular epithelial cells by stimulation of initiation phase of mRNA translation. We investigated if elongation phase of translation also contributes to high...
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Main Authors: | , , , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
American Society for Investigative Pathology
2007
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2111098/ https://ncbi.nlm.nih.gov/pubmed/17991718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070412 |
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