Activation of Glycogen Synthase Kinase 3β Ameliorates Diabetes-induced Kidney Injury

Increase in protein synthesis contributes to kidney hypertrophy and matrix protein accumulation in diabetes. We have previously shown that high glucose-induced matrix protein synthesis is associated with inactivation of glycogen synthase kinase 3β (GSK3β) in renal cells and in the kidneys of diabeti...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Mariappan, Meenalakshmi M., Prasad, Sanjay, D'Silva, Kristin, Cedillo, Esteban, Sataranatarajan, Kavithalakshmi, Barnes, Jeffrey L., Choudhury, Goutam Ghosh, Kasinath, Balakuntalam S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271222/
https://ncbi.nlm.nih.gov/pubmed/25339176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.587840
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